Morton's Neuroma presents with pain and numbness in which toes, typically worsened by tight footwear?

• A. Between the first and second toes
• B. Between the third and fourth toes
• C. Between the second and third toes
• D. Between the fourth and fifth toes

Answer: (B)

Morton’s neuroma is an irritation of the interdigital nerve as it passes between the metatarsal heads in the forefoot. The most common site is the web space between the third and fourth toes, where tight footwear can compress the nerve and elicit pain, numbness, or tingling. This pattern—forefoot discomfort localized to the space between the third and fourth toes and worsened by tight shoes or weight-bearing—is the classic presentation. Other interdigital spaces can be involved, but the third-to-fourth web space is the typical location doctors look for in this condition.